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Selective intracellular release of copper and zinc ions from bis(thiosemicarbazonato) complexes reduces levels of Alzheimer disease amyloid-beta peptide

Modern medical techniques are sometimes effective, but they can be costly, and success rates can vary

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cerebral hypoperfusion induces hypoxia and metabolic stress, activating kinases that hyperphosphorylate tau and accelerate NFT development 74

In the nigrostriatal tract system, dopamine undergoes autooxidation or oxidative deamination by monoamine oxidase-B, both of which aggravates with age, leading to increased production of peroxides and hydroxyl radicals 41