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3.1 VDRs and distribution Active form of vitamin D, 1,25-dihydroxyvitamin D (calcitriol), can cross the bloodbrain barrier and interact with vitamin D receptors (VDRs), which are found in brain areas involved in cognition, including the hippocampus, prefrontal cortex, amygdala, and thalamus (68)
Another CUR derivative, MitoCur-1 has been shown to significantly inhibit tumor growth by triggering ferroptosis in melanoma and enhancing sensitivity to vemurafenib-resistant cells
Chang H, Kuo CF, Yu TS, Ke LY, Hung CL, Tsai SY
Meanwhile, in Ayurvedic medicine, nourishing whole foods are used to help enhance the mood, fight fatigue, increase weight loss and improve digestion