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It uses the GLP-1/GIP dual incretin backbone (the same MAR709 chassis behind tirzepatide) instead of GLP-1 alone, which expands the targeted-cell population to include cells that express GIPR (most importantly, mature adipocytes)

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Thiazolidinediones (TZDs) Due to fluid retention and fat redistribution, rosiglitazone and pioglitazone are linked to 34 kg weight gain [45]

Researchers studying skin quality and tissue structure frequently investigate how different biological signals influence collagen production and maintenance