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The ighly ctive ntiretroviral herapy (HAART) is started with the combination of two nucleoside analogue transcriptase reverse inhibitors and one non-analogue nucleoside transcriptase reverse inhibitor or protease inhibitor plus ritonavir-boosted

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Vitamin B12 and folate (as N 5 -methyl-THF) are required for the methionine synthase reaction so a deficiency of either vitamin can result in homocysteinemia presenting with reduced levels of plasma methionine

Arch Biochem Biophys 314:284290 Chance B, Sies H, Boveris A (1979) Hydroperoxide metabolism in mammalian organs

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