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While the C-terminus of oxyntomodulin and the receptor ECD/ECL1 was lower resolution in the cryo-EM map, the interaction patterns in the modelled protein and the MD simulations were largely similar to GLP-1, albeit that the nature of some interactions differed due to their differing sequences

Similar content being viewed by others Introduction Globally, the number of patients diagnosed with autoimmune diseases is rising, driven by factors such as environmental exposures, genetic predisposition, and stress [1]