Withdrawal from GABAergic acting sedative-hypnotic drugs causes acute GABA-under-activity as well as glutamate over-activity which can lead to sensitization and hyper-excitability of the central nervous system, excito-neurotoxicity and increasingly profound neuroadaptions. Wikipedia Kindling (sedative-hypnotic withdrawal) Similarities Between Kindling in ME/CFS and Other Kindling Disorders ME/CFS shares many symptoms with benzodiazepine withdrawal syndrome including: agitation, chest pain, dizziness, fatigue and weakness, flu-like symptoms, irritable bowel syndrome, hot and cold flushes, orthostatic intolerance, restless leg syndrome, stiffness, tachycardia, sensitivity to touch and sound, indecision, etc
Because no human dose has been validated, any volume or concentration figure circulating in community sources is anecdotal rather than a documented protocol
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Both peptides arrive as lyophilized powder and must be stored at -20C before reconstitution
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