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Sensitivity or Allergies to B12 or Its Components: Some individuals may have an allergic reaction to the preservatives or additives in B12 injections, especially those with known sensitivities to certain medications or substances

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Wellness 20 July 2025 7 min read Needle Size for a B12 Injection: A Simple Guide By Alaiyka Parvez Owner, CoLaz Aesthetics Clinic The short version For an intramuscular B12 injection, the usual choice is a 22 to 25 gauge needle, 1 to 1.5 inches long, given at 90 degrees into the deltoid