OASIS 4 involved a 64-week treatment period, including a 12-week dose escalation period and a 7-week off-treatment follow-up period
What's measured, and how it's measured within these studies, can greatly vary the outcomes
Communication between perioperative teams and prescribing clinicians is particularly important when medication interruption is being considered, as discontinuation may require individualized management plans to maintain glycemic control and therapeutic effectiveness
However, this study has notable clinical limitations: The second cohort (Cohort 2) only included 24 patients, confounding factors such as diet and concurrent medications were not adjusted for, and there is a lack of clinically standardized protocols for MDSC function detection
If your tirzepatide arrives after being out of the fridge for an extended period, contact Prime Health to discuss whether the medication is still viable