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The CUD participants were recruited in this ancillary study from a wider sample of treatment-seeking patients participating in the Brainswitch project, a double-blind, sham-controlled trial testing the ability of repetitive transcranial magnetic stimulation to treat CUD (preliminary data published in Martinotti et al

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We appreciate commenters' suggestions to replace the quartile-based approach with a fixed benchmark or statistical outlier approach, as well as suggestions that the quartile-based approach would impact too many hospitals

12 min, each), the supernatants were membrane-filtered (0.2 m

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