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By activating both GIP and GLP-1 receptors, tirzepatide enhances insulin secretion in a glucose-dependent manner, suppresses glucagon release, slows gastric emptying, and reduces appetitecollectively improving glycaemic control and promoting weight loss

For ANDA submissions, Population Bioequivalence (PBE) analysis is required on the SAC data to demonstrate that the generic products dose delivery is statistically equivalent to the reference listed drug (RLD)

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Some people report feeling more energetic while taking Contrave, likely due to the bupropion component