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The review also highlighted preclinical evidence that GLP-1 receptor activation can counteract reactive oxygen species and mitigate oxidative cytotoxicityprocesses that accelerate cellular injury across multiple neurodegenerative pathways

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We ran three predictions for interactions of each candidate with the C-terminal region of SyeA (amino acids 174367) in AlphaFold3 ( 27 and averaged the interface predicted template modelling (ipTM) score for each (see Supplementary Dataset 7 at Figshare 17 )

Riesenberg et al., 2007)