More recent guidance suggests that 12 years may be sufficient for select patients, contingent on oncologic clearance and stable disease markers
The timeline does not support this mechanism
Lenzi A, Lombardo F, Sgro P, Salacone P, Caponecchia L, Dondero F, Gandini L
Theres evidence that polyunsaturated fatty acids like linoleic acid may act directly and indirectly on 5-alpha reductase by 1) reducing inflammation, and 2) altering lipid bilayers in cell membranes to decrease 5-alpha reductase formation
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