By facilitating the entry of fatty acids into mitochondria via the carnitine palmitoyltransferase 1 (CPT1) complex, it stimulates their oxidation and causes a decrease in cell volume
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Taken together, these efficacy and safety observations suggest that, for older patients without CV disease with T2DM who are not at A1C target despite metformin monotherapy, it is reasonable to preferentially recommend a DPP-4 inhibitor rather than an SGLT2 inhibitor as add-on therapy
[DOI] [Google Scholar] 43.Elbarbary N.S., Ismail E.A.R., El-Naggar A.R., Hamouda M.H., El-Hamamsy M
These programs also include medical oversight and, in many cases, lifestyle support to make progress sustainable