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This extension period allows your system to acclimate without compromising safety or adherence

Patients typically start with a lower dose of Wegovy, which is gradually increased over 16-20 weeks to minimize potential side effects such as nausea, vomiting, and diarrhea

Side effects from semaglutide (nausea, constipation) typically resolve within 48 weeks, whereas phentermine risks persist with long-term use

How Dosage Escalation Affects Your Weight Loss Speed Semaglutide therapy follows a structured dose escalation schedule starting at lower weekly injections and increasing gradually to a therapeutic maintenance dose over 4 to 5 weeks

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