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Some patients may experience shifts in blood sugar, joint stiffness, or fatigue, which is why regular followup and dose adjustments are important

Toxicity/ Side effects High doses of niacin supplementation have been found to reduce LDL and VLDL levels and to increase HDL levels and thus can be used to treat hypercholesterolemia and hypertriglyceridemia

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However, the appetite-suppressing effects of Ozempic may take a few days to become noticeable, and the degree of change can differ from person to person

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