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For example, if a certain substance is known to greatly slow down one of these enzymes, then any drug broken down by that enzyme will be present in the bloodstream in far higher amounts, leading to overdose

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Notably, the levels of urine SAM serve as a discriminative factor, enabling the differentiation between patients with mildly decreased kidney function and those with moderate to severe renal impairment

In peptide and protein analysis, mass spectrometry is often paired with chromatographic methods to improve the specificity of analytical characterization [11], [13]

10.1016/j.diabres.2021.108935 Diabetes Res Clin Pract