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27 Several, non-enzymatic cofactors like TAFs, mediators, and numerous enzymatic cofactors like the histone-modifying cofactors (histone deacetylase, histone acetyltransferase, histone methyltransferase, histone demethylase) and ATP-dependent chromatin-remodeling cofactors (SWI/SNF, ISWI, Mi-2/NuRD, and INO80/SWR1 families) have been discovered since

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Other interventions, such as fenofibrates enhancement of fatty-acid oxidation, have shown renal benefit in observational research and warrant further assessment

Strange RC, Lear JT, Fryer AA