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A recent Google Trends analysis revealed a significant increase in public interest in these drugs for off-label cosmetic use

Metformin, thiazolinediones (TZDs), glucagon-like peptide-1 receptor agonists (GLP1-RA), and dipeptidyl peptidase 4 (DPP-4) inhibitors are medications commonly prescribed for glycemic and weight control (Pozzi et al., 2019)

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