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Normalizing for time, retatrutide produces approximately 0.5% body weight loss per week at its highest dose, compared to roughly 0.25% for semaglutide and 0.31% for tirzepatide

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It is great to have new tools added to our toolbox to deal with obesity, Zhaoping Li, MD, the chief of the Division of Clinical Nutrition at UCLA Health and director of the UCLA Center for Human Nutrition in Los Angeles, told Healthline in an earlier interview

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Significant weight loss from GLP-1 therapy may reduce levothyroxine requirements, necessitating regular thyroid function testing every 36 months during active weight loss