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The concentration of HC able to inhibit cell viability by 50% (i.e., IC50) was calculated using the least square fit of four parameter-sigmoidal curves executed using GraphPad Prism (v

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Experimental cannabinoid 2 receptor activation by phyto-derived and synthetic cannabinoid ligands in LPS-induced interstitial cystitis in mice

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It has been demonstrated that DHA decreased the TLR-dependent inflammatory signalling pathway by inhibiting dimerization and the recruitment of receptors to lipid rafts, which resulted in the reduced production of pro-inflammatory cytokines [77,110]