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Hypertrophic adipocytes can promote the infiltration of macrophages into adipose tissue, thereby creating a local microenvironment characterized by a pro-inflammatory state, manifested by increased production of various cytokines, including tumor necrosis factor- (TNF-), interleukin-6 (IL-6), and chemokines

10.35946/arcr.v41.1.05 Alcohol Res

Ongoing studies continue to examine dual-pathway growth hormone stimulation, endocrine regulation, IGF-1 physiology, receptor signaling, and the coordinated biology of the hypothalamic-pituitary axis

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