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doi: 10.14814/phy2.12638 17 MarzookATomasAJonesB

Where semaglutide activates only GLP-1 receptors, tirzepatide activates both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors

Note: While this combination is safe for most, always consult with a healthcare professional before starting a new supplement routine, especially if you are pregnant, nursing, or taking medication for a specific health condition

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FIGURE 1 Next, to determine the neurotoxic effect of peroxynitrite on cultured SGNs, the cultured SGNs were treated with different concentrations (100 or 200 M) of peroxynitrite for 24 or 48 h, respectively (Figure 2A)