In people with both type 2 diabetes and obesity, an indirect comparison drawing on the separate SURMOUNT-2 (NCT04657003) and STEP 2 (NCT03552757) trials, rather than a single head-to-head study, reported weight reduction of up to 15.7% with tirzepatide and 10.6% with semaglutide 2.4 mg
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All pricing remains flat regardless of your dose levelyour dose may need to go up, but your price won't
Tirzepatide's additional GIP signaling may amplify gastric effects for some individuals, though GIP activation itself promotes satiety without direct nausea
Anghileri M, Miceli R, Fiore M, Mariani L, Ferrari A, Mussi C, et al