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One documented case involved a 45-year-old tennis player with a partial rotator cuff tear who had found limited relief from traditional treatments

Interestingly, the phospholipid metabolism is also possibly altered by riboflavin deficiency, because PLCA, an enzyme catalyzing the acylation of lysophosphatidic acid to form phosphatidic acid 35 , was up-regulated at the protein expression level in this study

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This leads to a phenomenon called "adipsia," or a lack of desire to drink fluids

Participants were from 131 medical research centres and hospitals across Argentina, China, Japan, Mexico, and the USA