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Doseresponse effects on HbA(1c) and bodyweight reduction of survodutide, a dual glucagon/GLP- 1 receptor agonist, compared with placebo and open-label semaglutide in people with type 2 diabetes: a randomised clinical trial

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From earlier work focused on muscular dystrophy conducted with former Penn Dental Medicine faculty member Elizabeth Barton, now at the University of Florida, the researchers believed that a particular form of IGF, a precursor of the protein that includes a separate component known as an e-peptide, was likely to stimulate regeneration better than mature IGF-1 that lacked the peptide

However, the research was done in rats, so more human studies are necessary to confirm this potential benefit