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It would happen a few hours after an injection, but only once or twice, then it would return to normal

The Phase 2 trial published in the New England Journal of Medicine studied doses ranging from 1mg to 12mg weekly

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Phase 3 protocols often begin at 2mg

In clinical and aesthetic settings, it is used off-label via injection or topical application to support collagen production, reduce fine lines and laxity, accelerate post-procedure recovery, and promote the bodys natural regenerative processes