doi: 10.1016/0306-4522(93)90175-F
However, previous studies have not investigated GLP-1 analogs and exendin 939 for pain transmission at peripheral sites, especially in small-sized nociceptive DRG neurons, where the TRPV1 channel is crucial in chronic pain-induced mechanical allodynia and thermal hyperalgesia 58,59,60,61
The mice were kept at a constant temperature (2325 C) and fed with a custom diet and water ad libitum
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To thoroughly assess any potential side effects associated with MT-II, such as changes in weight or general behavior, normal C57BL/6J mice underwent a longer, fourteen-day continuous ICV administration of MT-II at the same daily dose