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In the only direct evaluation of brain insulin resistance in PD, insulin signaling abnormalities were identified in the dorsolateral prefrontal and posterior parietal cortex of those with cognitive impairment, but not in those who were cognitively normal [72]
This outcome can be explained by the substantial weight loss and malabsorption that can follow bariatric surgery (6, 18, 20, 2325)
Amy Sheer, who runs a weight management clinic at University of Florida Health, says shes particularly glad to see the trial period extended it would be hard to see the health or medical cost benefits from a six-month pilot
