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Elderly persons tend to have a higher adipose to muscle tissue ratio, and this is therefore one reason why the half-life of some drugs, such as diazepam, is greater in the elderly

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doi:10.3390/nu14194002 Hobson, RM, Saunders, B, Ball, G, Harris, RC, Sale, C

Open questions in the GHK-Cu field include the specific cellular targets responsible for the broad transcriptomic effects, the relationship between the copper-delivery role and the direct peptide-only effects (if any), the comparative biology of GHK-Cu and related copper-peptides in defined cellular contexts, and the translation of cell-culture and animal-model findings to clinical-research endpoints under controlled study conditions