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All major GLP-1 RA trialsincluding LEADER, SUSTAIN-6, and FLOWwere sponsored by pharmaceutical companies (Novo Nordisk or Eli Lilly), raising the possibility of reporting bias

Dopamine neuron systems in the brain: an update

In a preclinical TBI model, ablation of this progression through antibiotic depletion of gut microbiota attenuated CA-1 (but not CA-3) neuronal loss, microgliosis, and associative learning deficits induced by CCI [112]

Common adverse reactions include nausea, diarrhea, vomiting, constipation, and abdominal discomfort, typically diminishing as the body adapts to the medication