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Diabetes Care 1997;20:18749.PubMed 13
(2020) demonstrated that the inhibitory effect of peroxisome proliferator-activated receptor gamma coactivator 1 (PGC1) on ROS induced by CP was mediated through TFEB-dependent autophagy
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Over time you can work up to 2 mg or 2.5 mg weekly depending on your goals and tolerance
( Generally, longer acting GLP-1RAs are more efficacious with respect to glycemic control than shorter acting GLP-1RAs
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![Mechanism of action of GLP-1 [25]](https://www.researchgate.net/publication/256289222/figure/fig1/AS:614177232142337@1523442671231/Mechanism-of-action-of-GLP-1-25.png)
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