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A "foundational challenge" was simply defining the substances because the chemical composition for peptides labeled with the same name varied considerably, explained FDA official Russell Wesdyk

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J Cereb Blood Flow Metab 25(2):177192 Haq E et al (2007) S -nitrosoglutathione prevents interphotoreceptor retinoid-binding protein (IRBP(161180))-induced experimental autoimmune uveitis