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Pain Modulation: DSIP is hypothesized to have analgesic-like properties, possibly by influencing opioid receptor activity and modulating pain signal transmission pathways

B12 injections are available on the NHS when clinically indicated following appropriate blood tests and diagnosis

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Unexplained hypercobalaminemia, particularly levels above 1,000 pg/mL, has been associated with liver disease, kidney dysfunction, myeloproliferative disorders, and certain solid cancers in multiple large-scale studies