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In particular cases, hypothyroidism may also be responsible for refractory gastrointestinal bleeding in routine treatment [144]

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Guinea pigs (Hartley, both sexes, 500-700 g b.w.) with whole body plethysmography, urethane anesthesia (1.5 g/kg i.p.), artificial ventilation under constant pressure (0.98 kPa), and relaxation of skeleton musculature by suxamethonium (0.2 mg/kg i.v.) were used in the present experiments

I mean, Novo got priced to the moon just based on what you're talking about, just demand is going to go up exponentially over the next couple years