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Kidney Disease, Dehydration Risk, and Medication Interactions Severe kidney disease (estimated glomerular filtration rate below 30) creates complications because GLP-1 medications concentrate in renal tissues

Consult your dentist or pharmacist for recommendations

This typically resolves within 6-12 months as weight stabilizes, and adequate protein and micronutrient intake can minimize the effect

A lower potency and a more nourishing base will help your skin adjust to the tretinoin and minimize the common side effects of irritation, dryness, redness, and peeling