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BMJ, 388, e079421
In fact, phase-specific VIM DBS has been shown to achieve tremor suppression with much less energy requirement [194]
Across our case studies for these drugs, we observe the following trends: Patent Term Extensions: Statutory Patent Term Adjustment (PTA) and Patent Term Extension (PTE) mechanisms delay the entry of generic medicines and add billions in additional revenue for blockbuster 2 drugs, even before accounting for any extended market monopoly as a result of follow-on patenting
It also acts as a free radical scavenger [8,11,75,110,133,134,135] in vascular occlusion/occlusion-like failure studies, in particular [40,41,42,43,47,48,49,50,51,52,53,54,55,56], associated with its function as a stabilizer of cellular junction [11], leading to the significantly mitigated leaky gut syndrome [11]