USA 109 , 25332538 (2012)
2023 Oct;93(5):401-409
Apart from the potent GH-releasing action, ghrelin has other actions including stimulation of lactotroph and corticotroph function, influence on the pituitary gonadal axis, stimulation of appetite, control of energy balance, influence on sleep and behavior, control of gastric motility and acid secretion, influence on exocrine and endocrine pancreatic function as well as on glucose metabolism, cardiovascular actions and modulation of proliferation of neoplastic cells, as well as of the immune system
On September 18, 2025, Roche agreed to acquire 89bio for up to ~$3.5 billion, adding the late-stage MASH candidate pegozafermin to strengthen its cardiometabolic pipeline
Storage requirements affect product quality throughout its lifecycle