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Whilst gallbladder-related concerns exist with rapid weight loss, previous cholecystectomy is not a contraindication to Wegovy use

### Conservative 24-Week Titration Protocol | Weeks | Weekly Dose | Notes | |-------|-------------|-------| | 14 | **1mg** | Starting dose

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Then, d-allulose (1 g kg 1 , 10 ml kg 1 ) or saline (10 ml kg 1 ) was administered orally or intraperitoneally at 60 min prior to each test