If were slowing the rate of gastric emptying (and thus how quickly the body gets rid of waste), theres going to be a risk of constipation
Mol Metab 2022;63:101533 114
Obesity 33(3):452462 [DOI] [PMC free article] [PubMed] [Google Scholar] 81.Lincoff AM, Brown-Frandsen K, Colhoun HM, Deanfield J, Emerson SS, Esbjerg S et al (2023) Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes
In recent years, extensive literature has reported that a variety of signaling pathways and transcription factors are involved in the fat differentiation process of WAT, such as the NOS pathway, neuropeptide S [87] pathway, SIRT1 [88] pathway, STAT3 [89], bone morphogenetic protein 4 (BMP4) [90] pathway, etc
These types of drugs are not recommended for people who have a family history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndromes, specifically types 2A or 2B