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doi: 10.1074/jbc.272.10.6663

Alongside the enhancing hepatic insulin/AKT signaling, PDK4 inhibition also activates the lipid AMPK/FOXO1/CD36 regulatory axis to promote liver regeneration by increasing fatty acid uptake

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CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer