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PVD occurs when narrowed blood vessels do not supply enough blood supply to muscles when needed most often muscles in the legs

However, the underlying mechanism remains unclear

doi: 10.1038/nprot.2007.44

[1] Retatrutide: What the Evidence Actually Shows Retatrutides pivotal obesity dataset is a Phase 2, double-blind, randomised, placebo-controlled trial in adults with obesity (or overweight plus a weight-related condition), testing once-weekly doses up to 12 mg over 48 weeks

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