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Low TSH serum level may trigger release of TRH from the hypothalamus with subsequent activation release of PRL from anterior pituitary in Covid-19

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Sadr-Azodi O, Sanders DS, Murray JA, Ludvigsson JF

In the developing brain, substantially high energy demand increases the need for glucose, oxygen and cerebral blood flow (Hagberg et al., 2014)

In this respect, the dual agonist effect of tirzepatide seems to give it a superiority on semaglutide, with a greater decrease (more than 2%) in glycated hemoglobin (A1c), a marker of chronic hyperglycemia (Figure 4)