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Therefore, the severity of AD is classified from mild to severe according to various clinical scales such as the Eczema Area and Severity Index (EASI), the Investigator Global Evaluation (IGA), the Three Item Severity Score (TIS), and the SCORing Atopic Dermatitis (SCORAD) scales (7)

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Dizziness upon standing, reduced urination frequency, or skin that doesn't bounce back quickly when pinched are more advanced warning signs requiring immediate attention

Reviews of human pharmacokinetics consistently describe 7-OH as a minor metabolite formed in the body, not a major constituent

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