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Efficacy of MEK inhibition in a recurrent malignant peripheral nerve sheath tumor

Interaction with NMDA and AMPA Receptors DSIP may modulate glutamatergic signaling , including NMDA and AMPA receptors, which are important in memory, stress response, and circadian regulation

-Synuclein interferes with synaptic vesicle trafficking, mitochondrial dynamics, and axonal transport, ultimately leading to synaptic dysfunction, impaired neurotransmission, and axonopathy

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