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Novo Nordisk may attempt to mitigate the impact from off-patent competition by protecting their share of Wegovy by enhancing weight-management services, or migrating patients from semaglutide to newer, patent-protected AOMs, including offering an oral version of semaglutide, effectively offering therapies with greater patient benefits

While further research is needed, liraglutide may work through various mechanisms, such as reducing inflammation in the brain, lowering insulin resistance and the toxic effects of Alzheimers biomarkers amyloid-beta and tau, and improving how the brains nerve cells communicate. Edison added that those in the study who received liraglutide had nearly 50% less volume loss in several areas of the brain, including frontal, temporal, parietal and total gray matter, as measured by MRI

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Regulatory bodies such as the EFSA have approved only a limited number of health claims for weight management ingredients, and even these are typically modest in scope

Sourlingas, D