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Possible side effects include: Injection site pain, redness, or bruising Unwanted facial or body hair growth Copper imbalance, which may cause headaches, nausea, or fatigue Flushing or histamine-type reactions in sensitive individuals Injectable copper peptides may not be appropriate for individuals with liver conditions, disorders of copper metabolism (such as Wilsons disease), or significant inflammatory sensitivity

Jennings L, Nestor L, Molloy O, et al

Topiramate commonly causes dizziness, fatigue, tingling sensations, and cognitive issues (brain fog), with more serious risks including metabolic acidosis and kidney stones

These reports, summarized in Table 1, provide sound evidence of the contributions of the gut microbiota and associated metabolites in CKD

Hamilton JW, Li BU, Shug AL, Olsen WA (julio de 1986)