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The use of peripheral -opioid receptor antagonists (PAMORA) in the management of opioid-induced constipation: an update on their efficacy and safety

For lasting results, patients usually require 8-10 sessions over a span of weeks

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So, um, it's a condition where, you know, we're learning new things every day, but, uh, despite all the remaining questions we do at this point, I would say have a roadmap in terms of how we might live to, you know, reduce our risk, if not prevent it altogether