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Funding Work supported by: Italian Ministry of University and Research PNRR-MUR NextGenerationEU PRIN 2022, cod

While this study did not include metformin as background therapy, it established tirzepatide's independent weight loss efficacy (up to 22.5% body weight reduction with the 15 mg dose at 72 weeks)

Weekly injections Starting at $400/vial As with all supplements and injections, GLP-1 medications should be used under the guidance of a qualified medical provider

Figure 9 4 Discussion The transition period and early lactation are among the most intensive and challenging time a dairy cow faces in life

With a 5-day half-life and steady-state accumulation of approximately 1.6-fold, the drug maintains consistent plasma levels throughout the dosing interval