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It has been proven safe and effective and has been shown to be relatively well tolerated among test patients according to a study published in the US National Library of Medicine/National Institutes of Health

The recommended dosage in patients with mild (eGFR of 60 89 mL/min/1.73 m 2) or moderate renal impairment (eGFR of 30-59 mL/min/1.73 m 2) is the same as those with normal kidney function [ see Clinical Pharmacology (12.3)]

Abortive infection is a desirable outcome, as it precludes disease development and has a low risk of onward transmission due to viral replication levels being below the PCR detection threshold

Balshaw, T