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But markets dont run on peak efficacy alone

PMID: 148 HammerichLBangenJMGovaereOZimmermannHWGasslerNHussSet al

K., Wu, Z

Endocrine-disrupting agents on healthy human tissues

Within adipocytes and skeletal muscle the PKC isoform, PKC/, phosphorylates proteins associated with intracellular vesicles containing the glucose transporter, GLUT4, resulting in their migration to, and fusion with, the plasma membrane